Why Peptides Are Key to Your Skincare Routine

Posted by Azadeh Shirazi MD on

What do peptides do in skin care? 

Peptides are short chain amino acids that work as signaling molecules to trick your skin into regenerating new collagen. Popular peptides hyaluronic acid and fibronectin both work to improve skin tone, firmness, and hydration. These restorative proteins stimulate the cellular renewal process to improve the appearance of wrinkles and fine lines in addition to enhancing the ability to hold onto water. 

All skin types can benefit from peptides. For normal skin types, peptides provide essential nourishment, helping to prevent premature aging and maintain healthy hydrated skin. In oily skin, peptides regulate oil production, as well as reduce the appearance of enlarged pores. Peptides also magnify hydration and strengthen the skin's moisture barrier benefiting those with dry skin types. Combination skin requires peptides to address multiple concerns like hydrating dry areas while also regulating oil production in the T-zone. Peptides are gentle and work well on sensitive skin types as they soothe and calm irritation while supporting the skin's natural repair processes.

Are ceramides or peptides better?

They are both beneficial but serve different roles in skincare. Ceramides are fatty lipids that hold our skin cells together thereby strengthening and restoring our skin barrier. Peptides help enhance skin hydration by attracting and holding onto water which strengthens the moisture barrier.

Can you use peptides every day?

Yes! Peptides have antioxidant properties that help protect the skin from environmental stressors such as UV radiation and pollution, which contribute to premature aging. By incorporating peptides into your daily skincare routine, you can effectively address multiple skincare concerns.

Dr. Azi Recommended Products:


Deeply hydrating cream formulated with one of the most powerful peptides, Tetrapeptide-21 to improve skin tone, texture, and the appearance of fine lines and wrinkles.  It’s more than a peptide cream as it also has Resveratrol to improve discoloration and sun damage, Niacinamide to brighten complexion, plant based stem cells, and ceramides to strengthen the skin barrier.  


A powerhouse of peptides in an eye cream - specially designed to cool and rejuvenate your under-eye area. With a lightweight formula, brighten, color correct, reduce puffiness, and protect against harmful UV rays with SPF 50.

Rhode Peptide Glazing Fluid

Lightweight and fast absorbing this peptide gel serum is formulated with niacinamide and marula oil to deeply hydrate the skin and soften fine lines and texture. 

Lancome Rénergie H.P.N. 300-Peptide Cream 

A daily moisturizer combining  over 300 different peptides along with Hyaluronic Acid and niacinamide to improve firmness, hydration, and fine lines.  Lightweight yet nourishing. Clinical studies found 86% of subjects reporting their skin appearing more youthful.

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Dr. Azadeh Shirazi, MD is a Board-Certified Dermatologist.

Specializing in medical, surgical, and cosmetic dermatology, Dr. Shirazi received her undergraduate and medical degrees from the University Of Kentucky College of Medicine. After doing a Research Fellowship at Harvard Medical School at the Wellman Center for Photomedicine, she completed her residency training in Dermatology and Cutaneous Surgery at the prestigious Mayo Clinic in addition to completing her training in dermatology and cosmetic surgery at the University of California San Diego.

She has received multiple research scholarships from iconic institutions including Harvard University and the University Of Texas Southwestern Medical Center and has several peer-reviewed publications to her name.